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Observe Carefully (1)modafinil raises levels of eluxadoline by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Observe. Being a precautionary measure because of incomplete info on the metabolism of eluxadoline, use caution when coadministered with solid CYP2C19 inhibitors.Coadministration of encorafenib with sensitive CYP3A4 substrates m

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